Dr. Bill Dawson

Dr. Bill Dawson


Program Emphasis

Our laboratory works on the molecular genetics of virus-host interactions and methods to control diseases caused by Citrus tristeza virus (CTV).  We have developed CTV into a tool to help find methods to control citrus canker and greening.

Education

University of Georgia, 1966, BS in Chemistry

Specialization

University of Georgia, 1971, PhD in Plant Pathology

Past Positions

1991-1992 University of California Presidential Chair in Plant
Dept. of Plant Pathology
Riverside, CA 92521

1984-1991 University of California Professor
Dept. of Plant Pathology
Riverside, CA 92521

1978-1984 University of California Associate Professor
Dept. of Plant Pathology
Riverside, CA 92521

1972-1978 University of California Assistant Professor
Dept. of Plant Pathology
Riverside, CA 92521

Additional Information

J. R. and Addie S. Graves Endowed Chair in Citrus Biotechnology

Refereed publications

Tatineni, S., Robertson, C. J., Garnsey, S. M., Bar-Joseph, M., Gowda, S., and Dawson, W. O.  2008.  Three genes of Citrus tristeza virus are dispensable for infection and movement throughout citrus trees.  Virology (in press).

Folimonov, A. S., Folimonova, S. Y., Bar-Joseph, M., and Dawson, W. O.  2007.  A stable RNA virus-based vector for citrus trees.  Virology 368: 205-216.  PDF

Weng, Z., Barthelson, R., Gowda, S., Hilf, M. E., Dawson, W. O., Galbraith, D. W., and Xiong, Z.  2007.  Persistent infection and promiscuous recombination of multiple genotypes of an RNA virus within a single host generate extensive diversity.  PLoS ONE 2: e917.

Borovsky, D., Rabindran, S., Dawson, W. O., Powell, C. A., Iannotti, D. A., Morris, T. J., Shabanowitz, J., Hunt, D. F., DeBondt, H. L., and DeLoff, A.  2006.  Expression of Aedes trypsin-modulating oostatic factor on the virion of TMV:  A potential larvicide.  Proc. Natl. Acad. Sci. USA 103: 18963-18968.

Robertson, C. J., Garnsey, S. M., Satyanarayana, T., Folimonova, S., and Dawson, W. O. 2005. Efficient infection of citrus plants with different cloned constructs of Citrus tristeza virus amplified in Nicotiana benthamiana protoplasts.  Proc. 16th Conference of the IOCV 16: 187-195.

Satyanarayana, T., Robertson, C. J., Garnsey, S. M., and Dawson, W. O. 2005.  Generation of a genetically engineered MCA13 nonreactive variant of the T36 decline isolate of Citrus tristeza virus. Proc. 16th Conference of the IOCV 16: 33-43.

Gowda, S., Satyanarayana, T., Robertson, C. J., Garnsey, S. M., and Dawson, W. O. 2005. Infection of citrus plants with virions generated in Nicotiana benthamiana plants agroinfiltrated with a binary vector based Citrus tristeza virus.  Proc. of the 16th Conference of the IOCV 16: 23-33. 

Ayllón, M. A., Satyanarayana, T., Gowda, S., and Dawson, W. O.  2005.  An atypical 3'-controller element mediates low-level transcription of the p6 subgenomic mRNA of Citrus tristeza virus.  Mol. Plant Pathol. 6:165-176.  PDF

Rabindran, S., Robertson, C., Achor, D., German-Retana, S., Holt, C., and Dawson, W. O.  2005.  Odontoglossum ringspot virus host range restriction in Nicotiana sylvestris maps to the replicase gene.  Mol. Plant Pathol. 6:439-447.

Satyanarayana, T., Gowda, S., Ayllón, M. A., and Dawson, W. O.  2004.  Closterovirus bipolar virion:  Evidence for initiation of assembly by minor coat protein and its restriction to the genomic RNA 5' region.  Proc. Natl. Acad. Sci. USA 101:799-804.

Ayllón, M. A., Gowda, S., Satyanarayana, T., and Dawson, W. O.  2004.  Cis-acting elements at opposite ends of the Citrus tristeza virus genome differ in initiation and termination of subgenomic RNAs.  Virology 322:41-50.

Albiach-Martí, M. R., Grosser, J. W., Gowda, S., Mawassi, M., Satyanarayana, T., Garnsey, S. M., and Dawson, W. O.  2004.  Citrus tristeza virus replicates and forms infectious virions in protoplasts of resistant citrus relatives.  Mol. Breed. 14:117-128.

Lu, R., Folimonov, A., Shintaku, M., Li, W-X., Falk, B. W., Dawson, W. O., and Ding, S-W. 2004.  Three distinct suppressors of RNA silencing encoded by a 20-kb viral RNA genome. Proc. Natl. Acad. Sci. USA 101:15742-15747.  PDF

Gowda, S., Ayllón, M. A., Satyanarayana, T., Bar-Joseph, M., and Dawson, W. O.  2003.  Transcription strategy in a Closterovirus:  A novel 5'-proximal controller element of Citrus tristeza virus produces 5'- and 3'-terminal subgenomic RNAs and differs from 3'-ORF controller elements.  J. Virol. 286:134-151.

Che, X., Dawson, W. O., and Bar-Joseph, M.  2003.  Defective RNAs of Citrus tristeza virus analogous to Crinivirus genomic RNAs.  Virology 310:298-309.

Bar-Joseph, M., Che, X., Mawassi, M., Gowda, S., Satyanarayana, T., Ayllon, M. A., Albiach-Marti, M. R., Garnsey, S. M., and Dawson, W. O.  2003.  The continuous challenge of Citrus tristeza virus molecular research.  Int. Org. Citrus Virol. 15:1-7.

Lee, R. F., Brlansky, R. H., Dawson, W. O., Roberts, P. D., and Timmer, L. W.  2003.  Florida Citrus Pest Management Guide:  Tristeza.  p. 93-95, 2003 Florida Citrus Pest Management Guide.  L. W. Timmer, ed.  University of Florida IFAS Extension SP-43.

Ayllon, M. A., Gowda, S., Satyanarayana, T., Karasev, A. V., Adkins, S., Mawassi, M., Guerri, J., Moreno, P., and Dawson, W. O.  2003.  Effects of modification of the transcription initiation site context on citrus tristeza virus subgenomic RNA synthesis.  J Virol. 77:9232-9243.  PDF

Satyanarayana, T., Gowda, S., Ayllon, M. A., and Dawson, W. O.  2003.  Frameshift mutations in infectious cDNA clones of Citrus tristeza virus: a strategy to minimize the toxicity of viral sequences to Escherichia coli.  Virology 313:481-491.

Gowda, S., Satyanarayana, T., Ayllón, M. A., Moreno, P., Flores, R., and W. O. Dawson.  2003.  The conserved structures of the 5' nontranslated region of Citrus tristeza virus are involved in replication and virion assembly.  Virology 317:50-64.  PDF

Olivares-Fuster, O., Fleming, G. H., Albiach-Martí, M. R., Gowda, S., Dawson, W. O., and Grosser, J. W.  2003.  CTV Resistance in transgenic Citrus based on virus challenge of protoplasts.  In vitro Cell. Dev. Biol. Plant 39:567-572.

Satyanarayana, T., Gowda, S., Ayllón, M. A., Albiach-Martí, M. R., Rabindran, S. and Dawson, W. O.  2002.  The p23 protein of Citrus tristeza virus controls asymmetrical RNA accumulation.  J. Virol. 76:473-483.

Satyanarayana, T., Gowda, S., Ayllon, M. A., Albiach-Martí, M. R., and Dawson, W. O.  2002. Mutational analysis of the replication signals in the 3'-nontranslated region of Citrus tristeza virus.  Virology 300:140-152.

Satyanarayana, T., Bar-Joseph, M., Mawassi, M., Albiach-Martí, M. R., Ayllón, M. A., Gowda, S., Hilf, M. E., Moreno, P., Garnsey, S. M., and Dawson, W. O.  2001.  Amplification of Citrus tristeza virus from a cDNA clone and infection of citrus trees.  Virology 280:87-96.  PDF

Karasev, A. V., Gowda, S., Bar-Joseph, M., and Dawson, W. O.  2001.  Closteroviruses.  p. 228-230, Encyclopedia of Plant Pathology, 2 Vol. Set.  O. C. Maloy and T. D. Murray, eds.  John Wiley & Sons, Inc.

Rabindran, S., and Dawson, W. O.  2001.  Assessment of recombinants that arise from the use of a TMV-based transient expression vector.  Virology 284:182-189.

Knapp, E., Dawson, W. O., and Lewandowski, D. J.  2001.  The conundrum of the lack of dRNAs associated with tobamovirus infections:  dRNAs that can move are not replicated by the wild-type virus; dRNAs that are replicated by the wild-type virus do not move.  J. Virol. 75:5518-5525.

Gowda, S., Satyanarayana, T., Ayllón, M. A., Albiach-Martí, M. R., Mawassi, M., Rabindran, S., Garnsey, S. M., and Dawson, W. O.  2001.  Characterization of the cis-acting elements controlling subgenomic mRNAs of Citrus tristeza virus:  production of positive- and negative-stranded 3'-coterminal and positive-stranded 5'-coterminal RNAs.  Virology 286:134-151.

Che, X., Piestun, D., Mawassi, M., Yang, G., Satyanarayana, T., Gowda, S., Dawson, W. O., and Bar-Joseph, M.  2001.  5'-Coterminal subgenomic rnRNAs in citrus tristeza virus-infected cells. Virology 283:374-381.

Peng, C-W., Peremyslov, V. V., Mushegian, A. R., Dawson, W. O., and Dolja, V. V.  2001. Functional specialization and evolution of the leader proteinases in the family Closteroviridae.  J. Virol. 75:12153-12160.

Mawassi, M., Satyanarayana, T., Gowda, S., Albiach-Martí, M. R., Robertson, C., and Dawson, W. O.  2000.  Replication of heterologous combinations of helper and defective RNA of citrus tristeza virus.  Virology 267:360-369.

Lewandowski, D. J., Dawson, W. O.  2000.  Functions of the 126- and 183-kDa proteins of tobacco mosaic virus.  Virology 271:90-98.

Chandrika, R., Rabindran, S., Lewandowski, D. J., Manjunath, K. L., and Dawson, W. O.  2000.  Full-length tobacco mosaic virus RNAs and defective RNAs have different 3' replication signals.  Virology 273:198-209.

Albiach-Martí, M. R., Mawassi, M., Gowda, S., Satyanarayana, T., Hilf, M. E., Shanker, S., Almira, E. C., Vives, M. C., López, C., Guerri, J., Flores, R., Moreno, P., Garnsey, S. M., and Dawson, W. O.  2000.  Sequences of citrus tristeza virus separated in time and space are essentially identical.  J. Virol.74:6856-6865.

Gowda, S., Satyanarayana, T., Davis, C., Navas-Castillo, J., Albiach-Martí, M. R., Mawassi, M., Valkov, N., Bar-Joseph, M., Moreno, P., and Dawson, W. O.  2000.  The p20 gene product of citrus tristeza closterovirus accumulates in the amorphous inclusion bodies.  Virology 274:246-254.

Mawassi, M., Satyanarayana, T., Albiach-Martí, M. R., Gowda, S., Ayllón, M. A., Robertson, C., and Dawson, W. O.  2000.  The fitness of Citrus tristeza virus defective RNAs is affected by the lengths of their 5'- and 3'-termini and by the coding capacity.  Virology 275:42-56.

Grdzelishvilli, V. Z., Chapman, S. N., Dawson, W. O., and Lewandowski, D. J.  2000.  Mapping the Tobacco Mosaic Virus movement protein and coat protein subgenomic RNA promoters in vivo.  Virology 275:177-192.

Satyanarayana, T., Gowda, S., Mawassi, M., Albiach-Martí, M. R., Ayllón, M. A., Robertson, C., Garnsey, S. M., and Dawson, W. O.  2000.  Closterovirus HSP70 homolog and p61 in addition to both coat proteins function in efficient virion assembly.  Virology 278:253-265.

Dawson, W. O., Satyanarayana, T., Gowda, S., Mawassi, M., Albiach-Martí, M. R., Ayllón, M. A., and Rabindran, S.  2000.  Development of a genetic system of the largest known plant virus, Citrus tristeza virus.  Proc. Int. Soc. Citricult.  IX Congr. 969-971.

Satyanarayana, T., S. Gowda, V. P. Boyko, M. R. Albiach-Marti, M. Mawassi, J. Navas-Castillo, A. V. Karasev, V. Dolja, M. E. Hilf, D. J. Lewandowski, P. Moreno, M. Bar-Joseph, S. M. Garnsey, and W. O. Dawson.  1999.  An engineered closterovirus RNA replicon and analysis of
heterologous terminal sequences for replication.  Proc. Natl. Acad. Sci. 96:7433-7438.  PDF